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    Neuroprotection Peptides

    Peptides studied for protecting neural tissue from damage.

    Selank

    Medium Evidence

    A synthetic peptide analog of tuftsin studied for anxiolytic and nootropic properties.

    Semax

    Medium Evidence

    A synthetic peptide derived from ACTH, studied for cognitive enhancement and neuroprotective effects.

    SS-31

    High Evidence

    A mitochondria-targeted peptide FDA-approved as FORZINITY (elamipretide) for Barth syndrome in September 2025 — the first FDA-approved mitochondrial-targeted therapeutic.

    Dihexa

    Low Evidence

    A hexapeptide analog studied for cognitive enhancement via hepatocyte growth factor pathway activation.

    Cerebrolysin

    Medium Evidence

    A porcine brain-derived peptide mixture approved in some countries for stroke recovery and neurodegenerative conditions.

    Semaglutide

    High Evidence

    A GLP-1 receptor agonist FDA-approved for type 2 diabetes and chronic weight management.

    NAD+

    Medium Evidence

    A coenzyme essential for cellular energy production, studied for anti-aging and metabolic support.

    Pinealon

    Low Evidence

    A short bioregulatory peptide studied for neuroprotective effects and cognitive support in aging.

    VIP

    Medium Evidence

    A neuropeptide with broad neuroimmune functions, studied for inflammatory conditions and nerve repair.

    CAQK

    Medium Evidence

    A brain-targeting tetrapeptide studied for neuroprotection and targeted drug delivery to injured brain and spinal cord tissue.

    P21

    Medium Evidence

    An 11-amino-acid CNTF-derived peptide studied for its ability to upregulate BDNF expression and promote neurogenesis in cognitive decline models.

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