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[Glossary](/glossary)/ Growth Hormone 

Basics 

# Growth Hormone

## Definition

A hormone produced by the pituitary gland that stimulates growth, cell reproduction, and cell regeneration.

## Why It Matters

Several peptides (CJC-1295, Ipamorelin) work by stimulating growth hormone release.

## Related Terms

[IGF-1](/glossary/igf-1)[Pituitary Gland](/glossary/pituitary-gland)[Secretagogue](/glossary/secretagogue)

## Related Peptides

[5-Amino-1MQ 

A small molecule NNMT inhibitor studied for metabolic enhancement and fat cell reduction.

](/peptides/5-amino-1mq)[Abaloparatide 

Abaloparatide (Tymlos) is a synthetic 34-amino-acid analog of parathyroid hormone-related protein, PTHrP(1-34), engineered to bind the PTH1 receptor with a strong preference for its transient RG conformation rather than the long-lived R0 conformation favored by teriparatide. That receptor bias produces a shorter burst of signaling per injection - enough to drive osteoblast activity, but short enough to limit the bone resorption and calcium mobilization that follow a prolonged signal. In the 18-month Phase 3 ACTIVE trial in 2,463 postmenopausal women, abaloparatide 80 mcg daily reduced new morphometric vertebral fractures by 86% versus placebo, alongside significant reductions in nonvertebral, major osteoporotic and clinical fractures. The FDA approved Tymlos in April 2017; in December 2021 the osteosarcoma boxed warning and the two-year cumulative lifetime limit were both removed from the label.

](/peptides/abaloparatide)[ACCG-2671 

An oral, once-daily small-molecule amylin receptor agonist in first-in-human Phase 1 testing for obesity — an early entrant in the race to make amylin biology available as a pill rather than an injection.

](/peptides/accg-2671)[Aleniglipron 

An oral non-peptide small-molecule GLP-1 receptor agonist achieving 16.3% placebo-adjusted weight loss at 44 weeks in Phase 2 ACCESS II, with Phase 3 on track for Q3 2026 after positive FDA end-of-Phase 2 feedback.

](/peptides/aleniglipron)

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