--- title: "Hormone Support Peptides | PepTracker Pro" description: "Peptides studied for supporting hormonal balance and endocrine function." lang: en json-ld: --- [Skip to main content](#main) **Educational information only.** This site does not provide medical advice. [Read full disclaimer](/disclaimer) [PepTracker Pro](/) [Home](/)[Peptides](/peptides)[Compare](/compare)[Glossary](/glossary)[Blog](/blog)[Calculators](/calculators)[Start Here](/start) [Open the App](https://app.peptrackerpro.com) [Peptides](/peptides)/ Hormone Support # Hormone Support Peptides Peptides studied for supporting hormonal balance and endocrine function. ### Abaloparatide High Evidence Abaloparatide (Tymlos) is a synthetic 34-amino-acid analog of parathyroid hormone-related protein, PTHrP(1-34), engineered to bind the PTH1 receptor with a strong preference for its transient RG conformation rather than the long-lived R0 conformation favored by teriparatide. That receptor bias produces a shorter burst of signaling per injection - enough to drive osteoblast activity, but short enough to limit the bone resorption and calcium mobilization that follow a prolonged signal. In the 18-month Phase 3 ACTIVE trial in 2,463 postmenopausal women, abaloparatide 80 mcg daily reduced new morphometric vertebral fractures by 86% versus placebo, alongside significant reductions in nonvertebral, major osteoporotic and clinical fractures. The FDA approved Tymlos in April 2017; in December 2021 the osteosarcoma boxed warning and the two-year cumulative lifetime limit were both removed from the label. [Bone Growth](/benefits/bone-growth)[rare-disease-treatment](/benefits/rare-disease-treatment)[Hormone Support](/benefits/hormone-support)[disease-modification](/benefits/disease-modification)+1 more [View Details](/peptides/abaloparatide) [\+ Compare](/compare?select=abaloparatide)[](https://app.peptrackerpro.com/?add=abaloparatide) ### HCG High Evidence A hormone used clinically for fertility treatment and testosterone support during hormone replacement therapy. [Hormone Support](/benefits/hormone-support)[Fertility](/benefits/fertility)[Sexual Health](/benefits/sexual-health) [View Details](/peptides/hcg) [\+ Compare](/compare?select=hcg)[](https://app.peptrackerpro.com/?add=hcg) ### HMG High Evidence A gonadotropin preparation containing FSH and LH, used in fertility protocols for both men and women. [Fertility](/benefits/fertility)[Hormone Support](/benefits/hormone-support) [View Details](/peptides/hmg) [\+ Compare](/compare?select=hmg)[](https://app.peptrackerpro.com/?add=hmg) ### Insulin Efsitora Alfa High Evidence A once-weekly basal insulin engineered as a single-chain insulin analog fused to an antibody (IgG2) Fc fragment, giving it a roughly 17-day half-life so a single subcutaneous injection covers a full week. Developed by Eli Lilly (code LY3209590, also called basal insulin Fc or BIF), efsitora is designed to replace daily long-acting insulin with a flat, ultra-stable weekly profile. In the large Phase 3 QWINT program it matched daily insulins glargine and degludec on A1C in type 2 diabetes, and in insulin-naive patients its simplified fixed-dose titration cut the number of dose adjustments dramatically while keeping hypoglycemia low. In type 1 diabetes (QWINT-5) it was non-inferior on A1C but showed a higher rate of severe hypoglycemia, a key safety caveat. As of mid-2026 efsitora is under FDA review for type 2 diabetes (a decision expected in the third quarter of 2026) and would compete directly with Novo Nordisk's once-weekly insulin icodec (Awiqli). [Glycemic Control](/benefits/glycemic-control)[Hormone Support](/benefits/hormone-support) [View Details](/peptides/insulin-efsitora-alfa) [\+ Compare](/compare?select=insulin-efsitora-alfa)[](https://app.peptrackerpro.com/?add=insulin-efsitora-alfa) ### Kisspeptin-10 Medium Evidence A neuropeptide that stimulates GnRH release, studied for fertility and reproductive hormone regulation. [Fertility](/benefits/fertility)[Hormone Support](/benefits/hormone-support)[Sexual Health](/benefits/sexual-health) [View Details](/peptides/kisspeptin-10) [\+ Compare](/compare?select=kisspeptin-10)[](https://app.peptrackerpro.com/?add=kisspeptin-10) ### Navepegritide High Evidence A C-type natriuretic peptide (CNP) analog FDA-approved in February 2026 for increasing linear growth in children with achondroplasia — the first once-weekly CNP therapy. [Joint Health](/benefits/joint-health)[Hormone Support](/benefits/hormone-support) [View Details](/peptides/navepegritide) [\+ Compare](/compare?select=navepegritide)[](https://app.peptrackerpro.com/?add=navepegritide) ### Oxytocin High Evidence A neuropeptide involved in social bonding, mood regulation, and reproductive functions. [Mood](/benefits/mood)[Anxiety Relief](/benefits/anxiety-relief)[Hormone Support](/benefits/hormone-support) [View Details](/peptides/oxytocin) [\+ Compare](/compare?select=oxytocin)[](https://app.peptrackerpro.com/?add=oxytocin) ### Palopegteriparatide High Evidence Palopegteriparatide (Yorvipath, developed as TransCon PTH) is Ascendis Pharma's once-daily prodrug of parathyroid hormone (1-34). An inert methoxy-PEG carrier is attached to PTH(1-34) through a TransCon linker that auto-cleaves at physiologic pH and temperature, releasing unmodified native-sequence PTH slowly enough to hold hormone levels inside the physiologic range for a full 24 hours. It is the first therapy approved as a true hormone replacement for chronic hypoparathyroidism rather than as an add-on to calcium and active vitamin D: in the Phase 3 PaTHway trial 78.7% of treated adults met a composite endpoint of normal serum calcium plus independence from conventional therapy at week 26, versus 4.8% on placebo. The FDA approved Yorvipath on August 9, 2024. [rare-disease-treatment](/benefits/rare-disease-treatment)[Hormone Support](/benefits/hormone-support)[Bone Growth](/benefits/bone-growth)[disease-modification](/benefits/disease-modification)+1 more [View Details](/peptides/palopegteriparatide) [\+ Compare](/compare?select=palopegteriparatide)[](https://app.peptrackerpro.com/?add=palopegteriparatide) Track Your Research with PepTracker Pro [Try the Free App →](https://app.peptrackerpro.com) [PepTracker Pro](/) Educational peptide information and research tracking tools. 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